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Peyronies-Management-Panel

Anti-Inflammation Panel 

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NAC

Boosting your body’s own Glutathione production

a powerful antioxidant

Eagle-DHA-Choline

A high DHA (Omega-3) formulation and optimal Choline suitable for everyone including pre and during pregnancy

EFA-Essentials

DHA – EPA – GLA

Ensuring broader-spectrum omega-3 support 

Supportive 

Comprehensive multi-vitamin, multi-mineral and trace element formulation to support cellular energy, biochemistry, molecular health, synthetic functions and biotransformation pathways

Targeted Products

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Bacillopeptidase-F: An anti-fibrin (anti-scar) agent

Boosting Nitric Oxide (NO)

Vitamin-D3 and Vitamin-K2 (MK7)

Vitamin-D3 and Vitamin-K2 (MK7)

FIND OUT MORE BELOW 

How does Bacillopeptidase-F work to prevent scarring in Peyronie’s Disease?:

This soy Natto fermented and purified enzyme helps fibrinolysis (scar dissolving) by decreasing PAI-1 this now allows Plasminogen to form Plasmin the scar-busting enzyme. Using this as soon as possible in the months after developing a painful lump and hopefully before the curvature begins may make a difference and even with early curvature using Bacillopeptidase-F along with the other modalities of management discussed here may just limit excessive scar formation and an increased curvature.

View the Bacillopeptidased-F Action Video Here: Click Here

Bacillopeptidase-F-Action

L-Citrulline: Effectively boosting Nitric Oxide (NO) to dilate blood vessels

The amazing L-Citrulline molecule provides far more L-Arginine than taking L-Arginine itself. Why? It is all about how these amino acids are absorbed and metabolised. L-Arginine is avidly taken up by the liver where the majority is converted to urea and ornithine leaving precious little for Nitric Oxide (NO) production.

L-Citrulline on the other hand is absorbed and taken to the kidneys where it is converted to L-Arginine and delivered directly into the blood stream thus by-passing the first-pass liver metabolism leading to much higher levels of L-Arginine systemically. This enables Nitric Oxide (NO) to be produced at optimal levels for blood vessel dilation and increased blood flow.

The sad part of this story is that the vast majority of doctors and specialists do not realise that for PDE5 Inhibitors to work they require Nitric Oxide which the PDE5 inhibitors don’t produce. Without Nitric Oxide these medications function poorly and can often fail. Click Here

Citrulline-NO-PDE5-Inhibitors
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Vitamin-K2 and the diversion of calcium away from the damaged penile area 

The damaged penile area can be infiltrated with calcium as this seems to be nature’s way of helping to either dampen down the inflammatory process or to stabilise the plaque. However, as is the case of many processes in the body, this healing process may be taken to a point not intended by nature and this is most likely due to the poor levels of Vitamin-K2 in most individuals consuming the Western diet.

In humans, the consumption of Vitamin-K1 in dark green leafy vegetables is converted by organisms in the gut microbiome to Vitamin-K2 but with a markedly decreased intake of vegetables and hence Vitamin-K1 the Vitamin-K2 is going to be very low and without Vitamin-K2 the ‘Calcium Cop’ that directs calcium away from soft tissues to bones then we are going run into abnormal calcification in damaged tissue.

Armed with the information above, it doesn’t take a genius to work out if around 95% of Western populations don’t get anywhere near the 5 servings of vegetables and 2 servings of fruit that Vitamin-K2 levels are going to be severely affected.

Click here to see how Vitamin-K2 in particular the MK7 form can help you.

Vitamin-K2-Action

Docosahexaenoic Acid or DHA

Omega-3’s that include DHA/EPA/ALA are critical for not only dampening down inflammation but also providing the structural integrity of cell membranes and supporting receptor sensitivity and many other functions.

Omega-3’s are not something to be taken lightly for long-term health benefits. The trick is the use of Omega-3’s long-term and not to use this in a pharmacological magic bullet sense to reverse decades of neglect. This is the folly of medical science trying to use nutrition in a heroic way in clinical care. Nutrition does not work like an accident and emergency drug! 

DHA is a vital component of the central nervous system making up 40% of the polyunsaturated fats of the brain and 60% of the retina1.

This huge makeup of DHA in neurological tissue should raise alarm bells that if this is deficient in nerves and nerve cells, that there will be a price to pay.

From tissue damage to trauma to ongoing diet-related insults to the body via oxidative stress, glycation, poor antioxidant intake, reduced phytochemical intakes, and exposures to environmental and toxic food compounds (herbicides, pesticides, phthalates, heavy metals, air pollution, toxicities in the home and many other threats). Omega-3’s are needed to fight off the damaging effect of inflammation and this fact cannot be disputed. Nobel Prizes have been awarded galore for Omega-3 research.

Choline: The Cholinergic Anti-Inflammatory Pathway 

Choline is a compound like DHA is essential in your diet. Choline is vital for cell integrity and cell signalling. Of critical importance is the Vagus nerve in dampening down systemic inflammation11. This nerve depends upon Acetylcholine which in turn depends on an adequate supply of Choline in the diet.

Vagus-N-Cholinergic-Antiinflammatory

We now know of the ‘Inflammatory Reflex’ where the brain detects an increase in pro-inflammatory cytokines and this, in turn, causes stimulation of the vagus nerve to dampen down cytokine release from macrophages in the spleen12,13. That the brain can dampen down inflammation through a nerve is an astounding finding and groundbreaking research. All of this depends on you getting an adequate supply of Choline often lacking in Western Diets

In 2019/2020 humanity, was introduced to SARS-CoV-2 (COVID-19) and a significant cause of death was a Cytokine Storm where a massive release of inflammatory cytokines caused death. This cytokine storm also occurs in seasonal flu. A lack of Omega-3’s, Choline and a multitude of other critical micronutrients in depleted Western diets will have caused ‘Sitting Ducks‘ in such a pandemic.

Choline is such as cheap essential nutrient and the ‘Elephant-in-the-room’ as a cause of lethal adverse effects of infections, and many disease processes is the Western diet riddled with inadequacies and ignorance, and yet medical science will look for a molecular mechanism with the ignorant belief that these cellular mechanisms are independent of dietary factors.

 

Two major phospholipids that are vital for cell membranes are phosphatidylcholine and sphingomyelin. Choline is needed to synthesise these components that enable cells to function.

The cell membrane is not only critical for cell-to-cell communication but for cell surface to cell interior communication through receptor activation by hormones, cytokines etc.

Choline is also vital in the creation of the neurotransmitter Acetylcholine, which is a target for Alzheimer’s treatments but when will medical science ever think of using the foundational molecule Choline to actually create Acetylcholine?

DHA: The Cochrane Collaboration finding on premature births

An unchallengeable fact is that life depends on your nutrition adequacy.

An amazing study by the Cochrane Collaboration a highly respected charitable organisation the looks objectively at medical research to reject non evidence-based ideas in the medical profession found that out of 70 randomised trials involving 20,000 women that DHA can reduce early preterm birth by 42% and by preterm birth overall by 11% an amazing result if you look at premature birth as a leading global cause of death and disability and a direct cause of more than 85% of perinatal deaths3. DHA helps with premature deaths through many mechanisms which share a commonality with neuroprotection or cellular integrity and protection of all cells, tissues and organs.

With such scientific evidence, it is imperative for medical practitioners to discuss these findings with women who are wanting to fall pregnant, especially when medical science trumpets evidence-based medicine as the gold standard for treatment.

So you can see the fantastic benefits of Omega-3’s and Choline and that these compounds need to be seriously considered in managing not only the brains of the mother and developing foetus and to prevent premature birth, but to use Omega-3’s and Choline in neurological disease and better still, to use this long before the manifestation of neurological disease starts.

DHA – EPA – GLA  

These anti-inflammatory components work synergistically with the DHA + Choline product above

This helps to balance the essential fatty acids by providing more EPA, some DHA and importantly GLA which is an Omega-6 compound with anti-inflammatory properties

Ensuring your cells have the right Omega-6 to Omega-3 ratio is vital to prevent an inflammatory overreaction to a threat

N-Acetyl Cysteine 

There is a growing role for NAC in neurological and mental health disorders

NAC increases a powerful antioxidant called Glutathione but there is growing evidence that NAC may work beyond the generation of Glutathione4.

NAC works in the following way4:

  1. Decrease inflammatory cytokines
  2. Increased Growth Factors
  3. Increased Neurite Formation through compounds like BDNF
  4. Decreasing oxidative (inflammatory) stress to nerve cells
  5. Neurotransmitter modulation

These are all vital neuroprotective effects and no wonder it is showing great promise in psychiatric diseases and neurodegenerative disorders.

Pharmaceutical Grade Product

This product has been designed to support mitochondrial bioenergetic mechanisms in many ways. It has also been designed to stimulate mitochondrial biogenesis i.e. to help stimulate new mitochondrial production.

This product contains the following

Filling in the Gaps: A good Multivitamin and Mineral Supplement

As I have made it known on this website, I find right-wing views on supplementation to be inane, and I am a medically trained practitioner.

There seems to be a myth out there that you can get all the nutrients you need from a ‘healthy diet’. However, in the real world 60 percent of people at least in many populations are overweight or obese putting those individuals at massive risk for a huge range of diseases including pandemics like COVID-19 killng obese, prediabetic diabetic, and hypertensive individuals to a far greater extent. So are these people eating a “healthy diet”?

Obesogenic diets are almost invariably calorie-rich and nutrient poor. Vegetable and fruit intakes have been shown to be consistently abysmally low in survey after survey in many countries to the tune of around 95 percent (95%) having insufficient intakes of fresh fruit and vegetables. Yes, this is the magnitude of people getting nowhere near the recommended intakes of fruit and vegetables the fresh foods where most people get their vital micronutrients. Once again, where is this mythical “healthy diet”?

Rigid statements are of no use to anyone in the real world.

Of growing concern now is the Triage Mechanism of nutrient insufficiency as mentioned above that may lead to a weakening of the body and impaired DNA repair processes, putting an individual at risk of cancer10. This triage mechanism is essentially robbing Peter to pay Paul, i.e. a shuffling of micronutrients from non-vital to vital organs enabling an individual to survive longer but in a weakened state.

For you, taking an excellent practitioner-only multivitamin every 2nd day will ‘fill in the gaps’ as stated by Harvard University and will help to ensure all your cellular biochemical and molecular systems function optimally. If your cells don’t function well, your tissues and organ systems become dysfunctional.

PROVIDING ACTIVATED B-GROUP VITAMINS AND MINERAL CHELATES FOR SUPERIOR ABSORPTION 

  1. Singh, M. (2005). “Essential fatty acids, DHA and human brain.” Indian Journal of Pediatrics 72(3): 239-242.
  2. Sanders, L.M. and Zeisel, S.H., 2007. Choline: dietary requirements and role in brain development. Nutrition today, 42(4), p.181.
  3. Middleton, P., Gomersall, J.C., Gould, J.F., Shepherd, E., Olsen, S.F. and Makrides, M., 2018. Omega‐3 fatty acid addition during pregnancy. Cochrane Database of Systematic Reviews, (11).
  4. Dean, O., Giorlando, F. and Berk, M., 2011. N-acetylcysteine in psychiatry: current therapeutic evidence and potential mechanisms of action. Journal of psychiatry & neuroscience: JPN, 36(2), p.78.
  5. Imai, S.-i. and L. Guarente (2014). “NAD+ and sirtuins in aging and disease.” Trends in cell biology 24(8): 464-471.
  6. Bonkowski, M. S. and D. A. Sinclair (2016). “Slowing ageing by design: the rise of NAD+ and sirtuin-activating compounds.” Nature Reviews Molecular Cell Biology.
  7. Hao, J., Ni, X., Giunta, S., Wu, J., Shuang, X., Xu, K., Li, R., Zhang, W. and Xia, S., 2020. Pyrroloquinoline quinone delays inflammaging induced by TNF‐α through the p16/p21 and Jagged1 signalling pathways. Clinical and Experimental Pharmacology and Physiology, 47(1), pp.102-110.
  8. Dibaba, D., et al. (2015). “Magnesium intake and incidence of pancreatic cancer: the VITamins and Lifestyle study.” British journal of cancer.
  9. https://www.hsph.harvard.edu/nutritionsource/multivitamin/
  10. Ames, B. N. (2006). “Low micronutrient intake may accelerate the degenerative diseases of aging through allocation of scarce micronutrients by triage.” Proceedings of the National Academy of Sciences 103(47): 17589-17594.
  11. Rosas‐Ballina, M. and Tracey, K.J., 2009. Cholinergic control of inflammation. Journal of internal medicine, 265(6), pp.663-679.
  12. Pavlov, V. A. and K. J. Tracey (2012). “The vagus nerve and the inflammatory reflex—linking immunity and metabolism.” Nature Reviews Endocrinology 8(12): 743.
  13. Bullmore, E., 2018. The inflamed mind: a radical new approach to depression. Picador.
  14. Lund, E. K., et al. (1999). “Effects of dietary fish oil supplementation on the phospholipid composition and fluidity of cell membranes from human volunteers.” Annals of Nutrition and Metabolism 43(5): 290-300.