The risk of insulin resistance is greatly underestimated. It is a major cause of vascular disease leading to heart attacks and stroke and peripheral vascular disease. It can be halted in its tracks through dietary management and the use of Metformin as has been shown in the Diabetes Prevention Program Outcomes Study (DPPOS) a long-term study on this deadly disease that affects close to 4 million people in Australia and around 86 million people in the USA.