Neurological RPS

DHA + Choline

Docosahexaenoic Acid or DHA is a vital component of the central nervous system making up 40% of the polyunsaturated fats of the brain and 60% of the retina¹.

This huge makeup of DHA in neurological tissue should raise alarm bells that if this is deficient that there will be a price to pay.

From dampening down inflammation, to providing structural integrity of a cell to receptor sensitivity and many other functions, Omega-3’s are not something to be taken lightly for long-term health benefits. The trick is the use long-term and not to use this in a pharmacological magic bullet sense to reverse decades of neglect. This is the folly of medical research and heroics. Nutrition does not work as an accident and emergency drug.

Choline

Choline is a compound like DHA is essential in your diet. Choline is vital for cell integrity and cell signalling. Choline is also vital in the creation of the neurotransmitter Acetylcholine which is a target for Alzheimer’s treatments but when will medical science ever think of using the foundational molecule Choline to actually create Acetylcholine?

Cochrane Collaboration finding on premature births 

An unchallengeable fact is that life depends on your nutrition adequacy.

An amazing study by the Cochrane Collaboration highly respected in the medical profession found that out of 70 randomised trials involving 20,000 women that DHA can reduce early preterm birth by 42% and by preterm birth overall by 11% an amazing result if you look at premature birth as a leading global cause of death and disability and a direct cause of more than 85% of perinatal deaths³. DHA helps with premature deaths through many mechanisms which share a commonality with neuroprotection or cellular integrity and protection of all cells, tissues and organs.

With such scientific evidence it is imperative for medical practitioners to discuss these findings with women who are wanting to fall pregnant especially when medical science trumpets evidence-based medicine as the gold standard for treatment.

So you can see the amazing benefits of Omega-3’s and Choline and that these compounds need to be seriously considered in managing not only the brains of the mother and developing foetus and to prevent premature birth, but to use Omega-3’s and Choline in neurological disease and better still, to use this long before the manifestation of neurological disease starts.

Pharmaceutical Grade Product

This product has been designed to support mitochondrial bioenergetic mechanisms in many ways. It has also been designed to stimulate mitochondrial biogenesis i.e. to help stimulate new mitochondrial production.

This product contains the following

This is a cutting-edge Vitamin-B3 compound

• It helps to restore age-related declines in NAD⁺ levels critical for energy production in the respiratory chain of mitochondria⁵.
• Nicotinamide Riboside activates Sirtuins which are longevity genes⁵ and is a highly researached front-runner in a group of Sirtuin Activating Compounds or STACs
• Australia’s Professor David Sinclair from the University of NSW and Harvard and MIT’s Professor Leonard P Guarente have written a number of papers on Sirtuin activation and STACs.
• A wonderful but complex paper on Nicotinamide Riboside, NAD⁺ and STACs was co-written by Prof David Sinclair⁶.

Pyrroloquinoline quinone (PQQ)

Another redox cofactor like NAD⁺

This compound has the amazing property of stimulating new mitochondria formation

When added to cultured human cells it was noted that PQQ is decreased cellular senescence (ageing)⁷.

Inflammaging is the process of increased inflammatory messenger molecules called cytokines as an individual gets older. This would undoubtedly be one reason for the higher risk for a Cytokine Storm in Influenza or COVID-19 in older groups. PQQ has been shown to block these effects as inflammation drives many chronic diseases such as Alzheimer’s, Parkinson’s, Cardiovascular Disease, Diabetes, many Cancers to name just a few of the inflammation-driven diseases that are common in society.

Putting the pieces together for an energy crisis

Magnesium Threonate (MgT)

This is an MIT researched molecule that has been shown to cross the Blood Brain Barrier (BBB) which is important for brain health.

Magnesium is involved in over 300 enzyme reactions

One critical and life-depending reaction is the production of ATP the energy currency in cells. ATP-Synthase is the enzyme involved in helping create ATP but needs magnesium in the process.

Diet may not be enough to provide the magnesium needed by the body⁸. This is where supplementation becomes vital especially in a vulnerable state like Alzheimer’s where there is a bioenergetic crisis brought about by the menopause.

Pancreatic cancer is also on the rise. Without consuming magnesium-rich foods such as dark green leafy vegetables where magnesium is at the heart of the chlorophyll molecule, the risk of pancreatic cancer jumps. This study showed that consuming less than 75 percent of the RDA for this mineral resulted in a huge 76 percent increase in the risk of pancreatic cancer⁸.

All these molecules will assist either through their antioxidant effects on the free radicals produced by mitochondria in the extraction of energy which can damage the cells that house the mitochondria and can damage the mitochondria themselves.

CoQ10 is a vital part of the respiratory chain that is a part of mitochondrial membranes and a lack of CoQ10 which also decreases in the aging process will weaken the bioenergetic processes of cells.

Filling in the Gaps: A good Multivitamin and Mineral Supplement

As I have made it known on this website, I find right-wing views on supplementation to be inane, and I am a medically trained practitioner.

There seems to be a myth out there that you can get all the nutrients you need from a ‘healthy diet’. However, in the real world 60 percent of people at least in many populations are overweight or obese putting those individuals at massive risk for a huge range of diseases including pandemics like COVID-19 killng obese, prediabetic diabetic, and hypertensive individuals to a far greater extent. So are these people eating a “healthy diet”?

Obesogenic diets are almost invariably calorie-rich and nutrient poor. Vegetable and fruit intakes have been shown to be consistently abysmally low in survey after survey in many countries to the tune of around 95 percent (95%) having insufficient intakes of fresh fruit and vegetables. Yes, this is the magnitude of people getting nowhere near the recommended intakes of fruit and vegetables the fresh foods where most people get their vital micronutrients. Once again, where is this mythical “healthy diet”?

Rigid statements are of no use to anyone in the real world.

Of growing concern now is the Triage Mechanism of nutrient insufficiency as mentioned above that may lead to a weakening of the body and impaired DNA repair processes, putting an individual at risk of cancer¹⁰. This triage mechanism is essentially robbing Peter to pay Paul, i.e. a shuffling of micronutrients from non-vital to vital organs enabling an individual to survive longer but in a weakened state.

For you, taking an excellent practitioner-only multivitamin every 2nd day will ‘fill in the gaps’ as stated by Harvard University and will help to ensure all your cellular biochemical and molecular systems function optimally. If your cells don’t function well, your tissues and organ systems become dysfunctional.