The critical nature of Vitamin-D3 and Vitamin-K2
There is no doubt that Vitamin-D3 is critical to help absorb Calcium from the intestine but the important fact to understand is that Vitamin-K2 is vital to guide that Calcium away from soft tissues, vascular linings and heart valves towards bones and other functions like clotting.
Redirection of Calcium by Vitamin-K2 to where it belongs: Vitamin-K2 is like the ‘Traffic Cop’ guiding calcium ‘traffic’ away from soft tissues like the vascular system, cardiac valves or soft tissue towards bone.
Proven Anti-Inflammatory Effects: Vitamin-D has proven anti-inflammatory modulation effects
Strong correlation with Insulin Sensitivity: Both Vitamin-D and Vitamin-K have a strong correlation with insulin sensitivity in double-blind,

controlled trials 21. Both Vitamin-D 21 and Vitamin-K 48 are strongly associated with insulin sensitivity with a new mechanism shown for Vitamin-K2 to improve mitochondrial function and utilization of glucose for energy production through SIRT1 signalling.
Prevention of Vascular calcification and Calcium Artery Calcium (CAC): Calcification of arteries can occur early in the life of an individual thus damaging the endothelium and increasing the risk of vascular disease and acute vascular outcomes such as heart attacks or strokes.
“Of the three forms of vitamin K, VK2 has been shown to exhibit profound effects on reducing vascular calcification 43.”
Vitamin-D + Calcium Supplements on their own may increase Serrated (Precancereous) Bowel Polyps:
When you hear doctors talk about osteoporosis, what is there ‘go to’ answer for such as complex problem “just take Vitamin-D PLUS Calcium” — one of the worst pieces of advice a doctor could give as bone health is far more than this simple solution. Calcium supplements with Vitamin-D on its own ignoring every other fat-soluble vitamin, including Vitamin-K2 the ‘Calcium Cop’ is dangerous advice. In a world where Magnesium intakes are so low, this creates a major problem as Magnesium is a natural antagonist of Calcium but if Mg is low, it allows Calcium to predominate. This calcium imbalance has been shown to increase the risk of metaplastic bowel polyps that are precancerous but also increases the risk greatly for vascular and heart valve calcification.
Magnesium a natural channel blocker: It is also important to know that Magnesium is a natural Calcium Channel Blocker once again decreasing the risk of vascular calcification so always ensure 1) a good all round Multivitamin and Mineral and extra Magnesium supplementation like Magnesium Threonate that crosses the Blood Brain Barrier (BBB)
Peyronie’s Disease of the Penis: The other problem with Peyronie’s Disease is that calcification of the penile plaque can occur which is known as ossification creating a stony rigidity of the damaged area and thus making it difficult to correct the curvature. Any male in the early stages of Peyronie’s needs to have Vitamin-D3 and K2 working for them along with all the other anti-inflammatory suggestions